Chroma only makes predictions, there's no substitute for real experience but luminosity values suggest that 1 W 445 blue will be dimmer than 100mw 532 green.
1W 445 blue = 28 lumens
0.1W 532 Green = 60 lumens
As for safety, lasers are a form of radiation and the higher the wattage the greater the irradiance.
There are international safety guidelines laid down by ILDA in the form of MPE and 10xMPE standards.
The only way to be sure you're safe is to take power meter readings based on pupil diameter exposure, convert these to mw/cm squared then compare these to the ILDA standard.
If they're above ILDA standards then you either need to expand the beam or reduce power or both until they're within safe limits.
Put in simple terms though, the lower the power the smaller the risk and the easier it is to comply with the safety standards.
This is a simpified view of it all and I suggest you look at the ILDA website in their freely available docs for Audience Scanning and the simple method.
What you were suggesting with a filter can be achieved in Pangolin Software by the use of BAM's (beam Attenuation Maps).
I'm sure others can explain it all in more depth to you or offer more practical help.